hfbHealth, Food & BiotechnologyHealth, Food & Biotechnology2712-7648РОСБИОТЕХ10.36107/hfb.2020.i2.s394hfb-42Research ArticleЗДОРОВЬЕHEALTHМикроархитектоника тканей плечевого сустава у собакThe microarchitecture of the tissues of the shoulder joint in dogsПавловскаяЕ. А.PavlovskayaE. A.

Павловская Екатерина Андреевна

ул. Ак. Скрябина, д. 23, с. 1, Москва, 109472

Ekaterina A. Pavlovskaya

st. Ak.  Skryabin,  23,  p.  1,  Moscow, 109472

vetgroomer@yandex.ruЛаптеваЕ. А.LaptevaE. A.

Лаптева Елена Александровна

Elena A. Lapteva

ФГБОУ ВО Московская академия ветеринарной медицины и биотехнологии – МВА им. К.И. СкрябинаРоссияMoscow State Academy of Veterinary Medicine and Biotechnology by K.I. SkryabinRussian FederationФГБОУ ВО «Московский государственный университет пищевых производств»РоссияMoscow State University of Food ProductionRussian Federation202005052021223445Copyright © Павловская Е.А., Лаптева Е.А., 20212021Павловская Е.А., Лаптева Е.А.Pavlovskaya E.A., Lapteva E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.hfb-journal.ru/jour/article/view/42

До  настоящего  времени  практически  не  изучены  особенности  формирования  хряща  в различных отсеках плечевого сустава у собак, а также зоны наименьшей устойчивости сочленения  в  целом.  Имеющиеся  исследования  в  основном  используют  визуальные методы диагностики, не применяя морфологических и морфометрических. Отсутствуют сведения о возрастных цитоморфологических преобразованиях, происходящих в суставе в норме и при патологии. В связи с этим целью нашего исследования явилось определить зоны  риска  возникновения  повреждения  плечевого  сустава  у  собак.  Исследования проводились  на  собаках  и  кадаверном  материале,  отобранном  от  гигантских,  крупных и  средних  пород.  Были  произведены  артроскопические  исследования  собак,  а  также световая  микроскопия  гистологических  срезов  свежеизвлеченных  образцов  тканей сустава. Вследствие травматизации сустава происходит трансформация физиологических синовиальных  складок  в  склерозированные  патологические  формы,  что  встречается у  немецких  овчарок  старше  5  лет  в  60%  случаев.  Процесс  минерализации  матрикса и  появление  множественных  очагов  окостенения  происходит  асинхронно  в  хряще головки  плечевой  кости  и  суставной  впадины  лопатки.  Остеопластические  процессы по  площади  сочленения  протекают  неравномерно.  Хрящевое  покрытие  суставной поверхности  лопатки  характеризуется  более  равномерным  распределением,  нежели суставная поверность головки плечевой кости. Определены зоны риска возникновения повреждения  структур  плечевого  сустава  у  собак.  К  ним  относятся:  краниальный  и медиальный  отсеки  сустава,  каудальная  область  хрящевого  покрытия  плечевой  кости, каудальная  область  суставной  поверхности  впадины  лопатки.  Полученные  данные восполняют сведения о диагностике и факторах риска в развитии патологий плечевого сустава  у  собак  крупных  и  гигантских  пород.  Их  целесообразно  использовать  при клинической диагностике и хирургии опорно-двигательного аппарата у животных.

Up  to  the  present  time  practically  not  studied  the  peculiarities  of  formation  of  cartilage  in the  various  compartments  of  the  shoulder  joint  in  dogs,  as  well  as  zones  of  least  resistance joints  in  General.  Available  studies  mainly  use  visual  diagnostic  methods,  without  applying morphological and morphometric. There is no information about age-related cytomorphological transformations  occurring  in  the  joint  in  normal  and  pathological  conditions.  In  this  regard, the aim of our study was to determine the zone of risk of damage to the shoulder joint in dogs. Studies were conducted on dogs and cadaver material, selected from giant, large and mediumsized  breeds.  Arthroscopic  studies  of  dogs  were  performed,  as  well  as  light  microscopy  of histological sections of freshly treated samples of joint tissues. As a result of trauma to the joint is transformed physiological synovial folds in sklerozirovanie a pathological form that occurs in German shepherd dogs over 5 years of age in 60% of cases. The process of mineralization of the matrix and the appearance of multiple foci of ossification occurs asynchronously in the cartilage of the head of the humerus and the articular cavity of the scapula. Osteoplastic processes in the area  of  articulation  occur  unevenly.  Cartilage  coating  of  the  articular  surface  of  the  shoulder blade is characterized by a more uniform distribution than the articular rotation of the humerus head. The zones of risk of damage to the structures of the shoulder joint in dogs were determined. These include: cranial and medial compartments of the joint, the caudal area of the cartilaginous coating of the humerus, the caudal area of the articular surface of the scapula cavity. The data obtained make up for the information about the diagnosis and risk factors in the development of shoulder joint pathologies in dogs of large and giant breeds. They should be used in clinical diagnosis and surgery of the musculoskeletal system in animals.

плечевой суставсобакатканьхрящкапсулакостьартроскопиямикроскопияплечевая костьлопаткаshoulder jointdogtissuecartilagecapsulebonearthroscopymicroscopyshoulder boneshoulder bladeReferencesAvtandilov, G. G. (1990). Medizinskaya morfometriya [Medical Morphometry]. Pearson.Coopman, F., Verhoeven, G., Saunders, J., Duchateua, L., & Van Bree H. (2008). Prevalence of hyp dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Veterinary Record, 29, 654–658.Avtandilov, G. G. (1990). Medizinskaya morfometriya [Medical Morphometry]. Pearson.Coopman, F., Verhoeven, G., Saunders, J., Duchateua, L., & Van Bree H. (2008). Prevalence of hyp dysplasia and humeral head osteochondrosis in dog breeds in Belgium. Veterinary Record, 29, 654–658.Davidson, P. T., Bullock-Saxton, J., & Lisle, A. (2008). Anthropometric measurements of the scapula, humerus, radius and ulna in labrador dogs with and without elbow dysplasia. Australian Veterinary Journal, 11, 425–428.Davidson, P. T., Bullock-Saxton, J., & Lisle, A. (2008). Anthropometric measurements of the scapula, humerus, radius and ulna in labrador dogs with and without elbow dysplasia. Australian Veterinary Journal, 11, 425–428.Ekman S., & Carlson C. S. (1998). The pathophysiology of osteochondrosis. Veterinary Clinics of North America Small Animal Practice, 28, 17-32.Ekman S., & Carlson C. S. (1998). The pathophysiology of osteochondrosis. Veterinary Clinics of North America Small Animal Practice, 28, 17-32.Smith, E. J., Marcellin-Little, D. J., Harrysson, O. L., & Griffith, E. H. (2016). Influence of chondrodystrophy and brachycephaly on geometry of the humerus in dogs. Veterinary and Comparative Orthopaedics and Traumatology, 3, 220–227.Smith, E. J., Marcellin-Little, D. J., Harrysson, O. L., & Griffith, E. H. (2016). Influence of chondrodystrophy and brachycephaly on geometry of the humerus in dogs. Veterinary and Comparative Orthopaedics and Traumatology, 3, 220–227.Hall, B. K., & Maintenance, A. (2005). Achon droplasia in: bones and cartilage: develop mental skeletal biology. Elsvier Academic Press, 226–358.Hall, B. K., & Maintenance, A. (2005). Achon droplasia in: bones and cartilage: develop mental skeletal biology. Elsvier Academic Press, 226–358.Hefti, F., Beguiristain, J., & Krauspe, R. (1999). Osteochondritis dissecans: a multicenter study of the European pediatric orthopedic society. Journal of Pediatric Orthopaedics Part B, 8, 231–245.Hefti, F., Beguiristain, J., & Krauspe, R. (1999). Osteochondritis dissecans: a multicenter study of the European pediatric orthopedic society. Journal of Pediatric Orthopaedics Part B, 8, 231–245.Johnson, D. R. (1977). The growth of femur and tibia in three genetically distinct chondrodystrophic mutants of house mouse. Journal of Anatomy, 125, 267–275.Johnson, D. R. (1977). The growth of femur and tibia in three genetically distinct chondrodystrophic mutants of house mouse. Journal of Anatomy, 125, 267–275.Kippenes, H., Johnston, G. (1998). Diagnostic imaging of osteochondrosis. Veterinary Clinics of North America Small Animal Practice, 28, 137–160.Kippenes, H., Johnston, G. (1998). Diagnostic imaging of osteochondrosis. Veterinary Clinics of North America Small Animal Practice, 28, 137–160.Mahirogullari, M., Chloros, G. D., Wiesler, E. R., Ferguson, C., & Poehling, G. G. (2008). Osteochondritis dissecanse of the humeral head. Joint Bone Spine, 75(2), 226–228.Mahirogullari, M., Chloros, G. D., Wiesler, E. R., Ferguson, C., & Poehling, G. G. (2008). Osteochondritis dissecanse of the humeral head. Joint Bone Spine, 75(2), 226–228.Markel, M. D., & Sielman, E. (1993). Radiographic study of homotypic variation of long bones in dogs. American Journal of Veterinary Research, 54, 2000–2003.Markel, M. D., & Sielman, E. (1993). Radiographic study of homotypic variation of long bones in dogs. American Journal of Veterinary Research, 54, 2000–2003.Mason, D. R., Schulz, K. S., Fujita, Y., Kass, P. H., & Stover, S. M. (2008). Measurement of hume roradial and humeroulnar transarticular joint forces in the canine elbow joint after hume ral wedge and humeral slide osteotomies. Veterinary Surgery, 37(1), 63–70. http://dx.doi.org/10.1111/j.1532-950x.2007.00349.xMason, D. R., Schulz, K. S., Fujita, Y., Kass, P. H., & Stover, S. M. (2008). Measurement of hume roradial and humeroulnar transarticular joint forces in the canine elbow joint after hume ral wedge and humeral slide osteotomies. Veterinary Surgery, 37(1), 63–70. http://dx.doi.org/10.1111/j.1532-950x.2007.00349.xMcCoy, A. M., Toth, F., & Dolvik, N. I. (2013). Articular osteochondrosis: a comparison of naturally-occuring human and animal disease. Osteoarthritis Cartilage, 21, 1638-1647.McCoy, A. M., Toth, F., & Dolvik, N. I. (2013). Articular osteochondrosis: a comparison of naturally-occuring human and animal disease. Osteoarthritis Cartilage, 21, 1638-1647.Morgan, J. P., Wind A., & Davidson, A. P. (1999). Bone dysplasias in the labrador retreiver: a radiographic study. Journal of the American Animal Hospital Association, 35(4), 322–340. http://dx.doi.org/10.5326/15473317-35-4-332Morgan, J. P., Wind A., & Davidson, A. P. (1999). Bone dysplasias in the labrador retreiver: a radiographic study. Journal of the American Animal Hospital Association, 35(4), 322–340. http://dx.doi.org/10.5326/15473317-35-4-332Nagura, S. (1969). Osteochondritis dissecans of the hip joint and its etiology [in German]. Arch Orthop Unfallchir, 65, 371–374. http://dx.doi.org/10.1177/2325967115570019Nagura, S. (1969). Osteochondritis dissecans of the hip joint and its etiology [in German]. Arch Orthop Unfallchir, 65, 371–374. http://dx.doi.org/10.1177/2325967115570019Ohlerth, S., Senn, S., Geissbühler, U., Kircher, P., & Flückiger, M. (2016). Prevalence of humeral head osteochondrosis in the greater swiss mountain dog and the border collie in Switzerland. Schweiz Arch Tierheilkd, 158(11), 749–754. http://dx.doi.org/10.17236/sat00091Ohlerth, S., Senn, S., Geissbühler, U., Kircher, P., & Flückiger, M. (2016). Prevalence of humeral head osteochondrosis in the greater swiss mountain dog and the border collie in Switzerland. Schweiz Arch Tierheilkd, 158(11), 749–754. http://dx.doi.org/10.17236/sat00091Omeliyanenko, N. P. (1991). Quantitative analysis of the ultrastructural organization of extracellular components in human articular cartilage. Clinic Orthopaedics, 34, 266.Omeliyanenko, N. P. (1991). Quantitative analysis of the ultrastructural organization of extracellular components in human articular cartilage. Clinic Orthopaedics, 34, 266.Omeliyanenko, N. P., Neverkovich, L. N., Sokolov, V. N. (1995). Ultrastructural analysis of the joint cartilage surface layer. In Proceedings of 5th Annual Meeting of the European Tissue Repair Society. (pp.105).Omeliyanenko, N. P., Neverkovich, L. N., Sokolov, V. N. (1995). Ultrastructural analysis of the joint cartilage surface layer. In Proceedings of 5th Annual Meeting of the European Tissue Repair Society. (pp.105).Pavlova, V. P., Kop’eva, T. P., Sluckii, L. I., & Pavlov, G. G. (1988). Hryashch [Сartilage]. Pearson.Petitt, R. A., Innes, J. F. (2008). Arthroscopic management of a lateral glenohumeral rupture in two dogs. In Proceeding of the 14th ESVOT Congress (pp.341).Pavlova, V. P., Kop’eva, T. P., Sluckii, L. I., & Pavlov, G. G. (1988). Hryashch [Сartilage]. Pearson.Petitt, R. A., Innes, J. F. (2008). Arthroscopic management of a lateral glenohumeral rupture in two dogs. In Proceeding of the 14th ESVOT Congress (pp.341).Prodromes, C. C., Ferry, J. A., & Schiller, A. L. (1990). Histological studies of the glenoid labrum from fetal life to old age. The Journal of Bone and Joint Surgery, 72(9), 1344–1348. http://dx.doi.org/10.2106/JBJS.18.01160Prodromes, C. C., Ferry, J. A., & Schiller, A. L. (1990). Histological studies of the glenoid labrum from fetal life to old age. The Journal of Bone and Joint Surgery, 72(9), 1344–1348. http://dx.doi.org/10.2106/JBJS.18.01160Rudd, R. G., Whitehair, J. G., & Marsolais, J. H. (1990). Result of management of osteochondritis dissecans of the humeral head of dogs: 44 cases. Journal of the American Animal Hospital Association, 26(2), 173–178.Rudd, R. G., Whitehair, J. G., & Marsolais, J. H. (1990). Result of management of osteochondritis dissecans of the humeral head of dogs: 44 cases. Journal of the American Animal Hospital Association, 26(2), 173–178.Seimering, G. B., & Eilert, R. E. (1986). Arthroscopic study of cranial cruciate ligament and medial meniscal lesions in the dog. Veterinary Surgery, 15(3), 265–269. http://dx.doi.org/10.1111/j.1532-950X.1986.tb00221.xSeimering, G. B., & Eilert, R. E. (1986). Arthroscopic study of cranial cruciate ligament and medial meniscal lesions in the dog. Veterinary Surgery, 15(3), 265–269. http://dx.doi.org/10.1111/j.1532-950X.1986.tb00221.xSemchenko, V. V. (2006). Gistologicheskaya tehnika [Histological Technique]. Pearson. Shea, K. G., Jacobs, J. C., Carey, J. L., Anderson, A. F., & Oxford, J. T. (2013). Osteochondritis dissecans knee histology studies have variable findings and theories of etiology. Clinical Orthopaedics and Related Research, 471(4), 1127-1136. http://dx.doi.org/10.1007/s11999-012-2619-6Semchenko, V. V. (2006). Gistologicheskaya tehnika [Histological Technique]. Pearson. Shea, K. G., Jacobs, J. C., Carey, J. L., Anderson, A. F., & Oxford, J. T. (2013). Osteochondritis dissecans knee histology studies have variable findings and theories of etiology. Clinical Orthopaedics and Related Research, 471(4), 1127-1136. http://dx.doi.org/10.1007/s11999-012-2619-6Shea, K. G., Jacobs, J. C., Grimm, N. L., & Pfeiffer, R. P. (2013). Osteochondritis dissecans development after bone contusion of the knee in the skeletally immature: a case series. Knee Surgery, Sports Traumatology, Arthroscopy, 21(2), 403–407. http://dx.doi.org/10.1007/s00167-012-1983-9Shea, K. G., Jacobs, J. C., Grimm, N. L., & Pfeiffer, R. P. (2013). Osteochondritis dissecans development after bone contusion of the knee in the skeletally immature: a case series. Knee Surgery, Sports Traumatology, Arthroscopy, 21(2), 403–407. http://dx.doi.org/10.1007/s00167-012-1983-9Slater, M. R., Scarlett, J. M., Karderly, R. E., & Bonnett, B. N. (1991). Breed, gender, and age as risk factors for canine osteochondritis dissecans. Veterinary and Comparative Orthopaedics and Traumatology, 4(3), 100-106. http://dx.doi.org/10.1055/s-0038-1633261Slater, M. R., Scarlett, J. M., Karderly, R. E., & Bonnett, B. N. (1991). Breed, gender, and age as risk factors for canine osteochondritis dissecans. Veterinary and Comparative Orthopaedics and Traumatology, 4(3), 100-106. http://dx.doi.org/10.1055/s-0038-1633261Sumner, D. R., Turner, T. M., & Galante, J. O. (1998). Symmetry of the canine femur: implications for experimental sample size requirements. Journal of Orthopaedic Research, 6(5),758–765. http://dx.doi.org/10.1002/jor.1100060519Sumner, D. R., Turner, T. M., & Galante, J. O. (1998). Symmetry of the canine femur: implications for experimental sample size requirements. Journal of Orthopaedic Research, 6(5),758–765. http://dx.doi.org/10.1002/jor.1100060519Uozumi, H., Sugita, T., Aizawa, T., Takahashi, A., Ohnuma, M., & Itoi, E. (2009). Histologic findings and possible causes of osteochondritis dissecans of the knee. American Journal of Sports Medicine, 37(10), 2003–2008. http://dx.doi.org/10.1177/0363546509346542Uozumi, H., Sugita, T., Aizawa, T., Takahashi, A., Ohnuma, M., & Itoi, E. (2009). Histologic findings and possible causes of osteochondritis dissecans of the knee. American Journal of Sports Medicine, 37(10), 2003–2008. http://dx.doi.org/10.1177/0363546509346542Van Bree, H. J. (1993). Comparison of the diagnostic accuracy of positive-contrast arthography and arthrotomy in evaluation of osteochondrosis lesions in the scapulohumeral joint in dogs. Journal of the American Veterinary Medical Association, 203(1), 84–88. PMID: 8407466Van Bree, H. J. (1993). Comparison of the diagnostic accuracy of positive-contrast arthography and arthrotomy in evaluation of osteochondrosis lesions in the scapulohumeral joint in dogs. Journal of the American Veterinary Medical Association, 203(1), 84–88. PMID: 8407466Van Bree, H. J., & Van Ryssen, B. (1998). Diagnostic and surgical arthroscopy in osteochondrosis lesions. The veterinary Clinics of North America: Small Animal Practice, 28(1), 161–189. http://dx.doi.org/10.1016/s0195-5616(98)50010-1Van Bree, H. J., & Van Ryssen, B. (1998). Diagnostic and surgical arthroscopy in osteochondrosis lesions. The veterinary Clinics of North America: Small Animal Practice, 28(1), 161–189. http://dx.doi.org/10.1016/s0195-5616(98)50010-1Van Gestel, M. A. (1985). Diagnostic accuracy of stifle arthroscopy in the dog. Journal of the American Animall Hospital Association, 21(1), 757–763.Van Gestel, M. A. (1985). Diagnostic accuracy of stifle arthroscopy in the dog. Journal of the American Animall Hospital Association, 21(1), 757–763.Van Ryssen, B., Van Bree, H. J., & Missinne, S. (1993). Successful arthroscopic treatment of shoulder osteochondrosis in the dog. Journal of Small Animal Practice, 34(10), 521–528. http://dx.doi.org/10.1111/j.1748-5827.1993.tb03529.xVan Ryssen, B., Van Bree, H. J., & Missinne, S. (1993). Successful arthroscopic treatment of shoulder osteochondrosis in the dog. Journal of Small Animal Practice, 34(10), 521–528. http://dx.doi.org/10.1111/j.1748-5827.1993.tb03529.xWood, M. C., Fox, D. B., & Tomlinson, J. L. (2014). Determination of the mechanical axis and joint orientation lines in the canine humerus: a radiographic cadaveric study. Veterinary Surgery Journal, 43(4), 414–417. http://dx.doi.org/10.1111/j.1532-950X.2014.12134.xWood, M. C., Fox, D. B., & Tomlinson, J. L. (2014). Determination of the mechanical axis and joint orientation lines in the canine humerus: a radiographic cadaveric study. Veterinary Surgery Journal, 43(4), 414–417. http://dx.doi.org/10.1111/j.1532-950X.2014.12134.xYtrehus, B., Carlson, C. S., & Ekman, S. (2007). Etiology and pathogenesis of osteochondrosis. Veterinary Pathology, 44(4), 429–448. http://dx.doi.org/10.1354/vp.44-4-429Ytrehus, B., Carlson, C. S., & Ekman, S. (2007). Etiology and pathogenesis of osteochondrosis. Veterinary Pathology, 44(4), 429–448. http://dx.doi.org/10.1354/vp.44-4-429Ytrehus, B., Ekman, S., Carlson, C. S., Teige, J., & Reinholt, F. P. (2004). Focal changes of blood supply during normal epiphyseal growth are central in the pathogenesis of osteochondrosis in pigs. Bone, 35(6), 1294–1306. http://dx.doi.org/10.1016/j.bone.2004.08.016Ytrehus, B., Ekman, S., Carlson, C. S., Teige, J., & Reinholt, F. P. (2004). Focal changes of blood supply during normal epiphyseal growth are central in the pathogenesis of osteochondrosis in pigs. Bone, 35(6), 1294–1306. http://dx.doi.org/10.1016/j.bone.2004.08.016Ytrehus, B., Haga, H. A., & Mellum, C. N. (2004). Experimental ischemia of porcine growth cartilage produces lesions of osteochondrosis. Journal of Orthopedic Research, 22(6), 1201–1209. http://dx-.doi.org/10.1016/j.orthres.2004.03.006Ytrehus, B., Haga, H. A., & Mellum, C. N. (2004). Experimental ischemia of porcine growth cartilage produces lesions of osteochondrosis. Journal of Orthopedic Research, 22(6), 1201–1209. http://dx-.doi.org/10.1016/j.orthres.2004.03.006Zhu, D., Carrig, C. B., Conners, R. W., & Swecker, W. S. (1992). Jr. Canine bone shape analysis by use of a radiographic image-classification system. American Journal of Veterinary Research, 53(7), 1090–1095. PMID: 1497175Zhu, D., Carrig, C. B., Conners, R. W., & Swecker, W. S. (1992). Jr. Canine bone shape analysis by use of a radiographic image-classification system. American Journal of Veterinary Research, 53(7), 1090–1095. PMID: 1497175

The authors declare that there are no conflicts of interest present.